Question Details
Mycoses Fungoides
by Chase Farm - June 19, 2009
Has any one had any success in treating this...I have a golden retreiver with ulcerated oozing, scalin hard lesion on her skin. Biopsy reveals T-cell lympnhoma. The difficulty is that it is hard to appreciate active acupuncture sites with all of her skin leaions. Her pulse i wiry and deep. Her tongue is red/pink. HEr appetite is decreased in the am since on her antibiotics. Her skin is non-puritic but erythematous. I was going to start Hoxsey- not a lot of damp or heat. Other ideas? thanks
Replies
by naturevet
June 18, 2009
Hi Jean,

We have one case right now that is relatively asymptomatic (i.e. lesions minimal) on a combination of low dose pred (<0.5 mg/kg) and Chai Hu jia Long Gu Mu Li Tang. That dog is into its 18th month since onset.

I've had two much milder cases respond to Blood tonic formulas, but I take it this dog is too severely affected for that.

Hope that helps you out.

Steve
by marneemadsen
June 19, 2009
Hey Jean,
I had a dog years ago with a complete cure from very same thing with high dose safflower oil alone. I found this dose on VIN - 3ml/kg, I assume daily. This was before I knew any Chinese Medicine, so I am sure you could do even better. Safflower is high in Omega 6's, so perhaps they are Qi Deficient in some way?

If pulse wiry and deep, and appetite off on abx, she may need her circulation to move toward the epeithelial surfaces and not driven away....

Good luck and see you soon!

Marnee
by bannink
June 21, 2009
Hi all,

I have a protocol for treatment of MF using high dose safflower oil (as Marnee suggested) and Vitamin A. You should use Hollywood brand safflower oil as it has the highest concentration of alpha-linoleic acid (according to my sources), which is the reason we are giving it. The protocol I have calls for 3ml/kg/wk divided into 2-3 doses, but I usually go higher than that because severe lesions can be very hard to calm down. There is also significant variation in fatty acid profile between brands. Conjugated linoleic acid is an omega 6 fatty acid which technically would be considered contraindicated in high doses in cancer patients but in a small study of dogs with MF they showed clinical improvement. There is much dissent among onco folks because many of us have not had much success with it, but I wonder if people maybe are not using the correct brand. And in my experience the severity of the lesions is correlated with the ability to see an appreciable response. I would also speculate that in Damp Heat cases it might not be a great idea to supplement really high levels of these omega 6 fatty acids.

Let us know how it goes.

Erin
by bannink
June 21, 2009
Oh, I meant to say conjugated linoleic acid in safflower oil.

Also, I would recommend using omega 3 fatty acid supplementation at the same time for their anti-inflammatory effects. It is never a good idea, in my opinion, to give omega 6 FA alone to dogs with cancer.

Erin
by Chase Farm
June 21, 2009
thanks guys I let you know. Jean
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