Question Details
Copper Toxicity In A Dog
by drklein - December 14, 2014    View Case Report
This dog has not responded to diet, herbs, or nutritional supplements - there is a large emotional component that may be interfering. Any suggestions for 'something' to try to change the direction this case is going in spite of everything short of conventional medicine.
Thanks, Susan Klein
Replies
by naturevet
December 24, 2014
Hi Susan,

We're a bit short in the nuances here that would guide prescription: pulse, tongue, 'emotions', signs and symptoms, prior prescriptions, side effects, etc.

In the absence of any information, and on the assumption that 'emotional' means anxious or aggressive, you can't go wrong with Xiao Yao San as a starter. Based on the response of liver enzymes to that formula, it should be more clear which path you need to go down

Steve
by drklein
December 31, 2014
Thanks for the reply - there is ALOT of info on this case so was trying to keep it simple! This dog was adopted from TX as a feral puppy - is very fearful of people & is extremely dog aggressive although it lives with an older Golden Retriever. P - 70 at exam - my interpretation is too much parasympathetic tone as this dog's pupils were quite dilated and she was completely withdrawn/shut down at exam. Pulses were good - a little thin and wiry on the R, bounding on the L. Tongue color was light purple. The symptoms consist of variable appetite and training difficulties. She seemed to be doing better over the past few years, then became more picky about food about 3 months ago. She has been on a rotating diet of raw and some high quality dry foods. Her owners are both experiencing their own health problems. They live on a ranch in the mountains. She has noise phobia and is restless at night - she moves around a lot at all times. Reverse sneezing is frequent and severe, choking/coughing after drinking water, and belching happen often. She had a difficult time recovering from her spay anesthesia as well as recently when she had a liver biopsy performed.
Owner is a CVT - annual preventative blood work 4/14 revealed ALT 334, AST 61. U/S showed small nodules on spleen - otherwise N. DX - acute insult, put on RX Hepato Support. Recheck labs 6 weeks later showed ALT 542, AST 64. Added sAME, Vit. E, & Vetriscience Liver Chews - DX changed to chronic hepatitis. She was also getting acupuncture txs at this time. Changes made - increased the Hepato Support, added alpha lipoic acid, NAC and Xiao CHai Hu Tang. Recheck labs 7/14 ALT 802, AST 141.
Liver biopsy done - inconclusive (slightly atypical reactive lymphoid hyperplasia with low to moderate cellularity) but copper levels 1020.00 (IDEEX - paraffin block - N 120-400, toxic >1,500).
Owner has been in contact with Dr. Twedt at CSU but has concerns about conventional treatments. She is currently doing a protocol with Standard Process Livaplex, Zn Liver Chelate, and Hepatrophin PMG for 12 weeks with a recheck lab done at that time. She is currently doing a low copper diet and Lakota's appetite is a bit better. She continues to remain symptom free although associated behavioral signs with copper toxicity do include many of the anxieties this dog exhibits - info extrapolated from effects on people.
Thoughts? Does the above herb still fit? Thanks!
by naturevet
January 21, 2015
Hi there,

Sorry for the delayed reply. I think it is a good fit. Blood deficiency can be aggravated in mid-summer, which XYS addresses. We've seen the formula work in similar cases in our own practice.

The choking behavior, throat issues, pupil dilation and aggression also make me think of homeopathic Lachesis, which can address Liver Blood and Yin deficiency. I'd add it in. Try 30C strength SID. You can source it from someplace like Whole Foods

Steve
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