Question Details
Aminocarpoic Acid
by Etpetdr - March 21, 2017
I just just saw a dog that was diagnosed with a ruptured hemangiosarcoma of the liver with pulmonary metastasis. Surgery was not recommended and the ER service sent her home with Aminocarpoic Acid and was told that this was the western version of Yunnan Baiyao. The only reference I can find about the use of Aminocarpoic Acid is for DM dogs. Are you familiar with anyone using this for HSA dogs? The dog is also on Yunnan and I recommended starting Xiao Chai Hu Tang. The owner wanted to make sure there is no problem giving the XCHT with the Aminocarpoic Acid. I personally have never used Aminocarpoic Acid so I have absolutely no experience with it. Has anyone heard of this? Is it safe to give with XCHT and Yunnan?

Thank you for your help!!!

Eleanor
Replies
by naturevet
March 21, 2017
Hi Eleanor,

It will be safe, but is unlikely to accomplish much. Certainly it is overstating things to say that EAC (epsilon aminocaproic acid) is the western version of Yunnan Bai Yao, since the latter is anti-cancer and EAC is not. EAC is used strictly as an anti-hemorrhage compound by inhibiting plasmin formation.

There's a study of EAC and YBY used together in HSA. Here is the URL of the abstract: https://www.ncbi.nlm.nih.gov/pubmed/27669112
There were no side effects at all.

For stage III dogs, we still use our protocol of Chai Hu Jia Long Gu Mu Li Tang, augmented with San Qi and Dang Gui; Yunnan Bai Yao; Yun Zhi (Coreolus granular whole herb extract at 30 mg/kg); and Vaccinium (Bilberry extract). It does seem to give decent survivals. If there are a lot of upper burner concerns, you can add in Modified Xue Fu Zhu Yu Tang. XCHT is helpful, but perhaps not as effective as CHJLGMLT.

Hope that helps!

Steve
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