Hi Cathy,
I'll share how I usually approach cases like this. Steve can chime in with his experience and whether he's had success with anything new, or different opinion.
Dang Gui Shao Yao San is one I often use for Damp, Blood deficient patients with stasis post splenectomy for HSA, along with a XCHT-based formula to address Shao Yang disharmony and the lack of mixing Yin/Yang in these patients with aggressive cancer. XCHT also contains a number of herbs which have biomedical rationale in the sense that they have demonstrated the potential to block tumor progression pathways recognized in canine HSA. To this, we have been adding Dang Gui (Angelica sinensis Root). This is a Blood tonic and will additionally help with blood deficiency along with having VEGF-inhibiting potential (anti-angiogenic). I'd probably add around 10-15g/100g base if you are using along with DGSYS which also contains Dang Gui. I've heard some people have had trouble with this being too moistening and causing diarrhea, but I haven't personally seen this problem. (The high dose Coreolus, though, I have seen cause diarrhea.) Steve also adds a robust amount of San Qi (as he doesn't usually also use Yunnan Pai Yao - unless this has changed recently). I usually also use Yunnan Pai Yao 2 caps BID for a dog this size.
For dogs with deeper pulses that may be weak, I usually opt for Chai Hu Jia Long Gu Mu Li Tang as the base formula (based on Steve's recommendations with the rationale of mobilizing Yang - and I agree that I've had some very deficient looking patients with deep weak pulses that do well on this formula), over Xiao Chai Hu Tang (which I use as a base in patients without heat signs who have more overtly wiry pulses).
I don't use a lot of tablet formulas because, in my hands, my patients tend to not do as well when I'm not robustly dosing and the Natural Path granular are relatively more potent...so maybe someone else could comment on dosing for you. I'd be concerned you may need to increase that, and would probably double your dose. For the granular formula I would usually use 3/4 tsp BID of each formula for a dog this size.
I typically also test vitamin D levels (I use the VDI test kit) and dose to achieve 100-120ng/mL. Rationale: In a 2016 veterinary study, low serum vitamin D3 levels were shown to be associated with an increased risk of developing splenic hemangiosarcoma in canine patients. The optimal serum vitamin D3 level was determined to be 100 -120 ng/mL based on iPTH and c-CRP variations plateauing at this level.
Reference: Selting KA, Sharp CR, Ringold R, et al. Serum 25-hydroxyvitamin D concentrations in dogs - correlation with health and cancer risk. Vet Comp Oncol. 2016 Sep;14(3):295-305.
Erin