Question Details
Help! Acute T Cell Now Bleeding
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I have a 9 year old Aussie SF with acute T cell lymphoma that was in remission with vincristine and pred then held with cytoxan, low dose pred, and hoxsey, vitamin A, and si maio san. Dog is in florida so I have not seen her, but she came out of remission with slowly elevating lymphocytes. Now her WBC's are almost all circulating blasts with a WBC count of 135,000 and low platelets and anemia. She started with a nose bleed yesterday and with low platelets and blasts thought she would bleed out. When she came out of remission, about 3 weeks ago, I doubled hoxsey and si maio san, played with cytoxan and increased pred...she feels great! But bloods look terrible, cells all blasts, low platelets, anemia...this is going to take her down. Help...can I add to her regime? Can I try another formula on top of si maio san and hoxsey...sorry I have no physical except cbc, hard enlarged LN (but not real bad) and a happy dog with cancer. I was planning from the conventional side to go to CCNU...we stopped cytoxan honing IT was surpressing rbc, neuts, and plate but now it appears bone marrow is full of the lymphoblasts and is "crowding out" all precursor cells of other lines....ASAP if you can anyone?
thank you...Donna
If I lose her it won't be for lack of effort on owner and dog's part and she has done so well with this, perhaps I can not ask for more?
Replies
by naturevet
October 28, 2009
Hi Donna,

Can you re-evaluate this dog from a TCM perspective? I take it the dog does not have Damp Heat as a cause of bleeding, given the formulas it is on, and the occurrence of bleeding despite that. So there are three other possiblities:

Qi not holding the Blood. The dog would have a weak or deep and wiry pulse, low appetite, fatigue, weakness, etc. Formula: Bu Zhong Yi Qi Tang. Points: BL 20, Sp 6, LV 13, GV 20, BL 15, BL 17, BL 18. Blood out of the nose would be watery

Blood stasis. The dog would have a wiry pulse, darkish tongue. Blood out of the nose would be dark or bright red. Formula: consider Xue Fu Zhu Yu Tang. Points: consider ST 37, 39; BL 17; BL 18

Blood Heat. Tongue would be red to dark red. Blood would be bright red. Dog may be heat intolerant. Pulse rapid deep and wiry. Points that would aid the pulse: GV3 or 4; GV 14; ST 36 (sedate); BL 17; LI 11. Formula: Qing Ying Tang.

In a case like this, where the diagnoses can be hard to differentiate, active points that change the pulse can really help figure the case out quickly. Qing Ying Tang is a blood moving formula, too, though and contains Huang Lian, which is an anti-leukemic. So if you've ruled out extreme deficiency, which should be pretty easy, then maybe just start with Qing Ying Tang.

Good luck!

Steve
by
October 28, 2009
Dog is voracious, but on 20mg pred. I will ask owner about heat cool preferences,etc and see if she can compare tongue to her other dogs...
She does not have access to an alternative practitioner...I'm it and feeling a bit inadequate not being able to put my hands on the dog. The blood was initially bright red, then thinned to pink and today a bit of dark blood. Would you continue Hoxsey and/or Si Miao San or stop both and go to the new formula. She did mention she has "blood shot" eyes, but I will see what I can get...we almost put her to sleep last night, but she ate this morning and was wagging her tail.
Thank you!
Donna
by naturevet
October 29, 2009
I guess I'd play the odds and go with Qing Ying Tang.

S
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