I've been treating a Damp Heat 4 year old spayed Bernese Mtn Dog for chronic recurrent e.coli infections of her bladder. She also has chronic renal insufficiency (azotemic and poorly concentrated USGs of 1.020). Ultrasound and x-rays are normal. Her vulva anatomy is normal. Maybe her low USGs due to her kidney disease prevent the body from naturally protecting itself from infections? When on Clavaseptin (amoxil/ clavulanic acid) she has no more E.coli (we always do lots of urine cultures with our urinalysis). I am thinking of starting her on evening doses of clavaseptin for 6 months. (when she was on that for 1.5 months, her uti cam back after discontinuing that). She is also on Si Miao San, cranberry, probiotics, Liu Jun Zi Tang, prescription diet k/d dry food with home cooked vegetables and meats, and fennel mixed into her food. Clinically she is totally normal- feels young and active since starting her herbs (less Damp and Hot). Her urine pH is 6. Just this darned recurrent e.coli UTI. Geesh! Shall I keep her on the current herbs and go for the 6 months of once daily clavaseptin? Maybe I should add in a Kidney Tonic like Rehmannia 8 to see if I can get her kidneys working better to improve her USG? Thank you very much! Julie