Question Details
Polyarthritis Of Unknown Origin
by tradcliffe - February 8, 2010
Alaina is a 7 yo FS overweight shepherd mix, whose owner observed her having trouble getting up in Nov'09, while seeming fine once she got moving. Her lumbar muscles were sensitive, there was some minor swelling of stifles, with sensitivity around patellae. I did not do a TCM exam at the time, the owner did think she was worse with the colder weather. She did improve significantly with NSAIDs.

Saw her again in Jan - she had improved somewhat on meloxicam, but was sore/slow without it, decreased appetite and weight loss. She was refusing to go up the stairs, owner had tried a glucosamine supplement and thought the dog was worse with it? Back legs are shaky, she spends most of her time on her dog bed by a heater. Her temp at that time was 39.4, tongue was lavender, popliteal lymph nodes were firm but still small, spleen felt enlarged but smooth. She was lethargic, and seemed painful in multiple joints - suspicion was Lyme disease.

Bloodwork was mostly normal, except for slightly increased ALP (309) and tbili (16). 4DX snap was neg for tick diseases. For financial reasons, dog was put on doxycycline for 4 weeks and meloxicam to watch for response. After 2 weeks, dog was doing much better according to owner, and at that time I started her on Xiao Chai Hu Jia Qin Jiao Tang, based on what I thought was a Shao Yang syndrome. A week later dog was having more trouble, appeared to me to be sore everywhere. We did Xrays of hips and stifles - no changes, joint taps of carpi, hocks and stifles and FNA of lymph nodes revealed very mild neutrophilic polyarthritis - like a low grade septic arthritis and reactive lymphoid hyperplasia. Tongue at this point - 1 month of doxycycline and meloxicam and 2 weeks of XCHJQJT is lavender, pulse is superficial, not easy to compress, wiry?

Now, as I look back on my notes on Bi Syndrome, I would classify her as a Painful Bi, and suspect my formula is too cooling - I was thinking too Western - thinking immune-mediated, fever, favorable response to NSAIDS and antibiotics = heat, ignoring the fact that she is heat seeking, and joints never felt warm, only swollen. So, I am thinking of changing to something like Du Huo Ji Sheng Tang to warm channels and eliminate cold? Or would you suggest something else? Yi Yi Ren Tang for Damp Bi, or Juan Bi Tang?
Replies
by tradcliffe
February 8, 2010
Just an update as I talked to the owner today - since we took the joint taps on Feb 2, she has been giving Meloxicam daily and the dog is back to normal. I thought she had done that in the past, but I misunderstood. Her appetite is back to normal, as is activity level and ability to move around. The only other thing she noticed were small papules on the inside of the pinnae near the head - she can feel them but not see them, and they do not bother the dog. She first saw them in mid-Dec after the dog had been out to a farm for a few days - she had also been out to that farm in October before the entire incident started. So, anyway, what I thought was only a partial response to NSAIDs seems to be an excellent response - hope that helps a little

Tracy
by naturevet
February 8, 2010
Hi Tracy,

I probably would have tried XCHT, too, if I'd been thinking Lyme's. In the absence of a response, we can set that aside.

My top choice for chronic inflammation, responsive to NSAIDs, in a dog that seeks warmth is Xiao Huo Luo Dan (Minor Invigorate the Collaterals).

How could have XCHT made things worse (if it really did)? I haven't seen this happen myself, but if the inflammatory process was still too acute, the immune stimulating and circulation mobilizing effects of the formula may have been too strong. So a lack of response then does not mean one in the future. All the same, though, I'd probably try XHLD given the salient features of the case.

Hope that helps. Let us know how it goes.

Steve
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